Choriocarcinoma syndrome in a case of abdominal testicular germ cell tumor with long‑standing bilateral gynecomastia

Anitha Mandava; Arvind K. Reddy; Krishna Mohan Mallavarapu; Veeraiah Koppula

doi:10.4103/wajr.wajr_21_23

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Published: 2025-06-03

DOI: https://doi.org/10.4103/wajr.wajr_21_23

Keywords:

Choriocarcinoma syndrome, computed tomography, gynecomastia, mammography

Anitha Mandava

1-7-139/75, S. R. K. Nagar, Risalagadda, Musheerabad, Hyderabad - 500 020, Telangana, India

Arvind K. Reddy

Departments of Radiodiagnosis, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana, India

Krishna Mohan Mallavarapu

Medical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana, India

Veeraiah Koppula

Departments of Radiodiagnosis, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana, India

Abstract

Choriocarcinoma syndrome is an extremely rare, life-threatening condition seen in patients having advanced choriocarcinomas with large tumor burden. We report an unusual case of choriocarcinoma syndrome wherein a long-standing bilateral gynecomastia was ignored and an underlying testicular malignancy undiagnosed.

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Issue

Vol. 30 No. 1 (2023): January - June

Section

Case Report

How to Cite

Mandava, A., Reddy, A. K., Mallavarapu, K. M., & Koppula, V. (2025). Choriocarcinoma syndrome in a case of abdominal testicular germ cell tumor with long‑standing bilateral gynecomastia. West African Journal of Radiology, 30(1), 26-28. https://doi.org/10.4103/wajr.wajr_21_23

References

1. Te Julián M, Pizarro E, Peralta SM, Vidal OG, Casals S, Ballestar E. Gynaecomastia as unusual presentation of primary choriocarcinoma of the colon: A case report and literature review. AACE Clin Case Rep 2015;1:e260‑4.

2. Pathak LK, Vijayaraghavan V, Ponder T, Dyrved NJ, Gandhi D. Acute clinical presentation of metastatic testicular choriocarcinoma: A case report and brief review of literature. J Med Cases 2014;5:639‑42.

3. Rejlekova K, Cursano MC, De Giorgi U, Mego M. Severe complications in testicular germ cell tumors: The choriocarcinoma syndrome. Front Endocrinol (Lausanne) 2019;10:218.

4. Mead GM, Stenning SP. IGCCCG International germ cell consensus classification: A prognostic factor‑based staging system for metastatic

germ cell cancers. International Germ Cell Cancer Collaborative Group. J Clin Oncol 1997;9:207‑9.

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