The Comparison of X-ray Attenuations of Contrast Media in Different Dilutions: An experimental Study
Article Sidebar
Views | PDF/EPUB Downloads:
79
/ 6
/ 7
Main Article Content
Abstract
Aims: Iodinated contrast materials are used as contrast material in radiologic examinations. There is an intense competition between the contrast media companies in the contrast market in areas such as price, effectivities, and lack of side effects. This experimental study was carried out for comparing the effectiveness of contrast agents. We measured X‑ray attenuations of contrast agents because image quality depends on these attenuation amounts.
Materials and Methods: Contrast agents are divided into two main groups in iodinated contrast materials; ionic‑iodinated contrast agents and nonionic‑iodinated contrast agents. Nonionic contrast materials are iopamidol, iohexol, iopromide, iobitridol, and iomeprol. In this study, by using contrast agents in different dilutions, X‑ray attenuations were examined in Hounsfield units by using computed tomography.
Results: There was no statistically significant difference between the slopes of five commercial forms according to dilutions.
Conclusion: From our study, we concluded that iopamidol, iohexol, iopromide, iobitridol, or iomeprol are same in clinical usage.
Downloads
Article Details
Section
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
How to Cite
References
1. Dooley M, Jarvis B. Iomeprol: A review of its use as a contrast medium. Drugs 2000;59:1169‑86.
2. McCormack PL. Iobitridol: A review of its use as a contrast medium in diagnostic imaging. Clin Drug Investig 2013;33:155‑66.
3. Rosati G. Clinical pharmacology of iomeprol. Eur J Radiol 1994;18 Suppl 1:S51‑60.
4. Bourin M, Jolliet P, Ballereau F. An overview of the clinical pharmacokinetics of X‑ray contrast media. Clin Pharmacokinet 1997; 32:180‑93.
5. ACR Manual on Contrast Media. Ver. 10.2. 2010. Available from: http://www.acr.org/quality-safety/resources/contrast-manual.
6. Pannu HK, Thompson RE, Phelps J, Magee CA, Fishman EK. Optimal contrast agents for vascular imaging on computed tomography: Iodixanol versus iohexol. Acad Radiol 2005;12:576‑84.
7. Thomson KR. Safe use of radiographic contrast media. Aust Prescr 2010;33:19‑22.
8. Hughes PM, Bisset R. Non‑ionic contrast media: A comparison of iodine delivery rates during manual injection angiography. Br J
Radiol 1991;64:417‑9.